• Shuveksha Rawat
• Anjali Bhatt
• Sunita Arya
• Sarika Devi
• Lokesh Tyagi

New born infection that is called neonatal sepsis remains as an important cause of morbidity and mortality among infants in developing countries accounting for 30-50% of total deaths each year. The present study was conducted in different Pediatric Department of tertiary care hospital of Dehradun, Uttrakhand, India. Mothers and caregivers participated in a personnel interview to gather clinical and demographic information. All the other information was collected from the case report form. A total of 250 neonates were enrolled in this study. Data were analyzed by using chi square test. In this study the incidence rate of neonatal sepsis was 32.05%. A total 250 neonates were studied, (males – 169 & females-81) out of which 159 (63.6%) cases were EOS and 91(36.4%) cases were LOS. Culture report found positive in 70 (28%) cases, while in 180 (72%) cases the culture report was negative. The predominant predisposing factors were , premature rupture of membrane 105(66.03%), low body weight 90(56.60%), Lack of breast feeding 58(63.73%),Low Apgar Score 80(50.31%), prolonged rupture of membrane 54 (33.96%), Aspiration of feed 47.25%, GI tract pathology 42(46.15%),while the major clinical feature of sepsis were Birth Asphyxia 61 (67.03%), Apnea 88(55.34%), Respiratory Distress 45 (49.45%). The most frequently identified pathogens in newborns with sepsis were Escherichia coli (12.90%) and Klebesella pneumonia (35.48%) in EOS and Escherichia coli (41.02%) and Candida (25.64%) in LOS. Place of residence, mother's educational attainment, maternal health (both before and after conception), and inadequate feeding were all statistically significantly correlated with the neonates' good culture results. According to the study's findings, socioeconomic variables significantly influence neonatal sepsis; thus, improving environmental factors, nutrition, mother education, and standard of living may also lower newborn mortality and morbidity.

Neonatal Sepsis, Socioeconomic Status, Culture Positive Sepsis, Tertiary care hospital

"Neonatal sepsis: the incidence rate of neonatal sepsis in different hospitals of Dehradun", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 2, page no.b79-b85, February-2025, Available :http://www.jetir.org/papers/JETIR2502111.pdf

"Neonatal sepsis: the incidence rate of neonatal sepsis in different hospitals of Dehradun", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 2, page no. ppb79-b85, February-2025, Available at : http://www.jetir.org/papers/JETIR2502111.pdf