• Kajal Mane
• Anuj Kadam
• Mrunalini Patil
• Pallavi Sutar

Finding a straightforward, sensitive, accurate, precise, and quick ultraviolet (UV) spectrophotometric method for estimating Efavirenz in its pure form, as well as its formulations and stability samples, is the goal of this progress report. These techniques were validated in accordance with ICH requirements, and the accuracy, precision, and ruggedness results were within acceptable bounds. During the recovery study, excipients did not intervene. The approach was also effective for estimating and quantitatively evaluating Efavirenz from formulation. A few recoveries that did not significantly depart from 100% showed that the procedures were reliable and accurate, and that the common excipients utilised in tablet formulation did not cause any problems. Pharmacopeias have suggested several ways to regulate the quality of Efavirenz, an antiretroviral medication used to treat AIDS. These methods rely on costly equipment that is sometimes unavailable in African nations. A sensitive, dependable, easy-to-use, and quick method for determining the active ingredient Efavirenz in Efavirenz tablets has been validated for the purpose of controlling their quality by verifying their dosage. This problem has been resolved by employing UV-visible spectrophotometry, a low-cost and user-friendly instrument that is accessible in many laboratories across the African continent. Repeatability and intermediate precision were used to calculate the accuracy. Consistency over a brief period of time in the same operational environment is implied by repeatability. The intermediate precision analysis is expressed in terms of laboratory variance on different days and analyst-to-analyzer variation by different analysts.

UV-visible spectrophotometry, Efavirenz, AIDS, Accuracy, Precision and Ruddedness.

"REVIEW ON METHOD DEVELOPMENT AND VALIDATION OF EFAVIRENZ AS A DOSAGE FORM BY UV SPECTROPHOTOMETER", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 3, page no.h417-h436, March-2025, Available :http://www.jetir.org/papers/JETIR2503752.pdf

"REVIEW ON METHOD DEVELOPMENT AND VALIDATION OF EFAVIRENZ AS A DOSAGE FORM BY UV SPECTROPHOTOMETER", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 3, page no. pph417-h436, March-2025, Available at : http://www.jetir.org/papers/JETIR2503752.pdf