• Dr. Wan- e-mi Laloo
• Dr. B Saravanan
• Dr. K L Virupaksha Gupta

Due to heavy industrialization and pollution, one constantly comes into contact with various pollutants. The intoxicated beverages, spicy and fast food, along with the repeated consumption of incompatible food, causes sensitivity towards allergens, leading to the release of antibodies and various types of allergic skin reactions like Urticaria. Sheetapitta share similar symptomatology as Urticaria. The incompatible diet and life style leads to the production of toxic substances in the body and causes the imbalance of dosha and even cause impaired agni. This may result in hyper sensitivity of body’s immune system, and triggers the allergic attacks. Sahasrayoga has mentioned Amritarajanyadi Kashaya in treating Sheetapitta. The information related to the ingredients, rasa panchaka etc of Amritarajanyadi Kashaya and phatho-physiology of Sheetapitta and Urticaria is collected from various Ayurvedic classic literature, Modern literature and digital database. This formulation contains properties like kandughna, kushtaghna, dahaprasamana, jvaraghana and even Deepana, Pachana properties and has pharmacological action like anti-inflammatory, anti-allergic, analgesic activities, etc. This review explores the probable mechanisms of Amritarajanyadi Kashaya in managing Sheetapitta, with an emphasis on its anti-histamine effects, such as inhibiting histamine release, blocking histamine receptors, and modulating pro-inflammatory cytokines. KEYWORDS: Amritarajanyadi Kashaya, anti-histamine effect, Sheetapitta, Urticaria

"EXPLORING THE EFFICACY OF AMRITARAJANYADI KASHAYA IN SHEETAPITTA W.S.R TO URTICARIA- A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 3, page no.i316-i328, March-2025, Available :http://www.jetir.org/papers/JETIR2503845.pdf

"EXPLORING THE EFFICACY OF AMRITARAJANYADI KASHAYA IN SHEETAPITTA W.S.R TO URTICARIA- A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 3, page no. ppi316-i328, March-2025, Available at : http://www.jetir.org/papers/JETIR2503845.pdf