• Dr. Ch. G. Gupta

Medicinal botany has developed into a vibrant discipline that combines ancient knowledge with contemporary scientific progress and global health. The ethnobotanical insights are being integrated with advanced scientific methodologies to develop effective treatments for various diseases and contributing discovery of novel therapeutic agents. The synergistic blend of traditional knowledge and modern technology for drug discovery, sustainable healthcare and biodiversity conservation. Traditional knowledge of medicinal plants is a vital resource of pharmaceutical development. Many contemporary drugs originate from plant-based discovery for treatment. Ethnopharmacology plays a crucial role in validating traditional claims and identifying active compounds. Documentation of knowledge is essential for preservation and preventing biopiracy, ensuring indigenous communities. Medicinal plants and their medicinal application for advancements in phytochemistry and computational methodologies. Current trend highlight the identification of bioactive substances by phytochemical methods including metabolomics and chromatography. Molecular biology techniques such as DNA barcoding and genomic analyses have improved the verification and comprehension of the metabolic processes of medicinal plants. Computational methodologies such as virtual screening, machine learning and ADMET analysis are expediting drug discovery by forecasting biological activity and enhancing phytochemical extraction. The ethnopharmacology consistently offers significant insights into conventional plant-derived treatments. The drug development, identification of novel therapeutic molecules and enhancement of established therapies. The ethnomedical resources to create standardized, efficacious, and safe pharmaceuticals. The amalgamation of phytochemistry examines chemical components of plants and computational techniques evaluate extensive datasets and forecast drug-target interactions and expediting the drug development processes. These developments highlight significance of multidisciplinary collaboration in the advancement of medicinal botany and environmental sustainability. This review emphasizes the integration of phytochemistry, biotechnology, and computational methods as pivotal elements in contemporary drug development.

Ethnopharmacology, phytochemistry, computational methodologies, ADMET analysis.

"Traditional Knowledge of Medicinal Plants is Used in Modern Science: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 9, page no.c225-c235, September-2025, Available :http://www.jetir.org/papers/JETIR2509228.pdf

"Traditional Knowledge of Medicinal Plants is Used in Modern Science: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 9, page no. ppc225-c235, September-2025, Available at : http://www.jetir.org/papers/JETIR2509228.pdf