• Ajay Balu Wadekar

Present research work deals with synthesis and antibacterial screening of novel 1(4-aminophen yl)-2(p-chlorophenyl thiocarbamido)-1-ethanol against different pathogenic bacterial strains. Throughout this work Gram-positive and Gram-negative pathogenic bacteria’s (like Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes and Proteus vulgaris) are used for evaluation of antibacterial activity by disc diffusion method at 0.002 to 0.01 concentrations range. The effect of the structure of the investigated compounds on the antimicrobial activity is discussed. it shows remarkable antibacterial activity against Escherichia coli (causes diarrhea) and Staphylococcus aureus (causes pus formation) and Proteus vulgaris (wound and urinary tract infections) while weakly act against Streptococcus pyogenes. The potency of the drug is increased due to substitution.

1(4-aminophenyl)-2-(p-chlorophenyl thiocarbamido)-1-Ethanol, Gram Positive bacteria, gram negative bacteria, antibacterial activities

"Synthesis and Antibacterial Screening of Novel 1(4-Aminophenyl)-2(p-Chlorophenyl Thiocarbamido)-1-Ethanol ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 9, page no.c711-c714, September-2025, Available :http://www.jetir.org/papers/JETIR2509279.pdf

"Synthesis and Antibacterial Screening of Novel 1(4-Aminophenyl)-2(p-Chlorophenyl Thiocarbamido)-1-Ethanol ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 9, page no. ppc711-c714, September-2025, Available at : http://www.jetir.org/papers/JETIR2509279.pdf