• Dr.Rajatha R.Rao
• Dr Mamatha V.Rao

ABSTRACT: Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and systemic features. In Ayurveda, it is comparable to Amavata, caused by the interaction of Ama and aggravated Vata. Bhavaprakasha Nighantu describes several Ekamoolika Prayogas (single-drug therapies) for its management. Objective: To review classical references and modern evidence on single drugs mentioned in Bhavaprakasha Nighantu for Amavata, and to assess their relevance in rheumatoid arthritis. Methods: A textual review of Bhavaprakasha Nighantu was carried out, focusing on drugs directly indicated in Amavata. Their Ayurvedic properties and therapeutic indications were correlated with the clinical features of RA. Supporting pharmacological and clinical research was also analyzed. Results: Seven Ekamoolika Dravyas—Shunthi (Zingiber officinale), Pippali (Piper longum), Chukra (Rumex vesicarius), Guggulu (Commiphora mukul), Sinduvāra (Vitex negundo), Eranda (Ricinus communis), and Nili (Indigofera tinctoria)—were identified. Each drug has specific indications: Shunthi and Pippali in painful conditions; Chukra, Eranda, and Nili in Jwara-associated cases; Shunthi, Guggulu, and Eranda in Shotha; Sinduvāra and Nili in Viruddhahara-induced disease; and Guggulu and Eranda in Sthoulya. Modern research highlights their anti-inflammatory, analgesic, antioxidant, and immunomodulatory effects, correlating with RA pathology. The link between gut dysbiosis, Ama formation, and autoimmunity further supports their therapeutic rationale. Conclusion: Bhavaprakasha Nighantu emphasizes the individualized use of Ekamoolika Prayogas in Amavata. Selecting appropriate drugs based on Nidana, Samprapti, and Lakshana provides a patient-specific approach that aligns with both Ayurvedic principles and modern understanding of RA. This integrative perspective highlights the contemporary relevance of classical Ayurvedic knowledge in autoimmune disease management.

Amavata, Rheumatoid Arthritis, Bhavaprakasha Nighantu, Ekamoolika prayoga

"Ayurvedic Management of Rheumatoid Arthritis (Amavata): A Review of Ekamoolika Prayoga from Bhavaprakasha Nighantu", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 9, page no.e106-e114, September-2025, Available :http://www.jetir.org/papers/JETIR2509413.pdf

"Ayurvedic Management of Rheumatoid Arthritis (Amavata): A Review of Ekamoolika Prayoga from Bhavaprakasha Nighantu", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 9, page no. ppe106-e114, September-2025, Available at : http://www.jetir.org/papers/JETIR2509413.pdf