• Dr.Pranita Uttamrao Ranveer
• Dr.Santosh T. Jatale
• Dr. Rajesh Vithalrao Sawai

Yashtimadhu (Glycyrrhiza glabra Linn.), one of the most revered herbs in Ayurveda, is frequently mentioned by Acharya Charaka in eleven different Mahakashayas, reflecting its diverse therapeutic importance. These include Jivaniya, Kanthya, Varnya, Sandhaiya, Kandughna, Mutra-Virajaniya, Sonita-sthapana, Chardinigrahana, Snehopaga, Vamanopaga, and Asthapanopaga Mahakashayas. Classical references highlight its role in promoting life span, rejuvenation, voice and throat health, complexion, wound healing, allergy and pruritus management, urinary disorders, hemorrhagic conditions, vomiting suppression, oleation therapies, and Basti karma support. From an Ayurvedic perspective, its Madhura rasa, Guru-Snigdha guna, Sheeta virya, and Madhura vipaka make it Pitta-Vata shamaka, Oja-promoter, Rasayana, and Balya. Modern pharmacology validates these classical claims, as Glycyrrhizin, glabridin, and flavonoids confer anti-inflammatory, anti-ulcer, hepatoprotective, immunomodulatory, demulcent,anti-pruritic, and wound-healing actions. The critical appraisal indicates that Charaka’s inclusion of Yashtimadhu across 11 Mahakashayas is not repetitive but reflective of its multidimensional pharmacological spectrum. Thus, Yashtimadhu stands as a paradigm where classical Ayurvedic wisdom and contemporary pharmacological evidence converge, justifying its relevance in integrative therapeutics.

Yashtimadhu, Glycyrrhiza glabra, Charaka Samhita, Mahakashaya.

"CRITICAL ANALYSIS OF THE ROLE OF “YASHTIMADHU” IN CHARKOKTA MAHAKASHAYA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 9, page no.e148-e154, September-2025, Available :http://www.jetir.org/papers/JETIR2509417.pdf

"CRITICAL ANALYSIS OF THE ROLE OF “YASHTIMADHU” IN CHARKOKTA MAHAKASHAYA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 9, page no. ppe148-e154, September-2025, Available at : http://www.jetir.org/papers/JETIR2509417.pdf