• Dr . Ashish Bobade
• Dr. Harshali Pimpalshende

The Ayurvedic concepts of Puriṣadhara Kala and Asthidhara Kala represent vital functional membranes involved in digestion and tissue formation. This critical analysis explores these two Kalas in relation to calcium absorption and metabolism, integrating Ayurvedic principles with modern biomedical understanding. Puriṣadhara Kala, located in the colon, aligns with the mucosal lining of the large intestine where fermentation of dietary fibers by gut microbiota produces short-chain fatty acids (SCFAs), enhancing passive calcium absorption. Asthidhara Kalā, associated with bone tissue (asthi dhatu), corresponds to the sites of calcium deposition and bone remodeling processes governed by osteoblast activity and hormonal regulation. The study highlights the interconnectedness of gut health and skeletal strength, emphasizing that optimal functioning of both Kalas is essential for maintaining calcium homeostasis. This integrative approach underscores the relevance of classical Ayurvedic anatomy in understanding complex physiological processes such as mineral absorption and bone metabolism.

Purishdhara Kala, Asthidhara Kala, Calcium absorption, oestoblast.

"Critical Analysis of “Purishdhara Kala sa evum Asthidhara Kala” with Special Reference to Calcium Absorption. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 10, page no.b514-b516, October-2025, Available :http://www.jetir.org/papers/JETIR2510171.pdf

"Critical Analysis of “Purishdhara Kala sa evum Asthidhara Kala” with Special Reference to Calcium Absorption. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 10, page no. ppb514-b516, October-2025, Available at : http://www.jetir.org/papers/JETIR2510171.pdf