• Dr. Amit Kumar
• Pooja Bishnoi

Background: Infertility (Bandhyatva) is a global health concern affecting approximately 10–15% of couples in the reproductive age group. While anatomical, genetic, endocrine, and lifestyle factors are well recognized, psychological stress has emerged as a significant but often underdiagnosed contributor. Stress not only impairs reproductive physiology but also creates a vicious cycle where infertility itself intensifies psychological distress. Objective: This review aims to critically analyze the impact of psychological stress on infertility from both Ayurvedic and modern scientific perspectives, exploring their points of convergence and potential for integrative management. Methods: A comprehensive literature review was conducted using classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Kashyapa Samhita) alongside modern medical databases (PubMed, Scopus, Google Scholar). Relevant studies from 2004–2024, focusing on stress and reproductive health, were included. Conceptual mapping was performed to correlate Ayurvedic principles such as Manasika Bhava, Dosha vitiation, Ojas depletion, and Satvavajaya Chikitsa with modern mechanisms including HPA axis activation, cortisol imbalance, oxidative stress, and psychoneuroendocrine dysfunction. Results: Findings indicate that chronic psychological stress impairs fertility through hypothalamic–pituitary–gonadal (HPG) suppression, oxidative stress, and behavioral disruptions. Ayurveda similarly attributes Bandhyatva to disturbances in Beeja, Kshetra, Ritu, and Ambu, aggravated by negative Manasika Bhava such as Chinta (worry), Shoka (grief), and Bhaya (fear). Strong correlations exist between stress-induced cortisol elevation and Agni vitiation, oxidative stress and Ojas depletion, as well as mind-body therapies and Satvavajaya Chikitsa. Conclusion: Psychological stress plays a pivotal role in infertility, both as a causative and perpetuating factor. Ayurveda and modern science, though differing in terminology, converge in recognizing the mind–body connection in reproductive dysfunction. Integrative management strategies—including Satvavajaya Chikitsa, Rasayana therapy, Panchakarma, yoga, and modern stress-reduction techniques—hold promise for improving reproductive outcomes. Further clinical trials combining Ayurvedic and biomedical approaches are needed to validate these correlations and enhance evidence-based fertility care.

Bandhyatva; Infertility; Psychological Stress; Ayurveda; Manasika Bhava; Ojas; Hypothalamic–Pituitary–Adrenal Axis; Cortisol; Oxidative Stress; Satvavajaya Chikitsa; Rasayana; Integrative Medicine.

"Impact of Psychological Stress on Bandhyatva A Correlative Study in Ayurveda and Modern Science", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 10, page no.c584-c592, October-2025, Available :http://www.jetir.org/papers/JETIR2510275.pdf

"Impact of Psychological Stress on Bandhyatva A Correlative Study in Ayurveda and Modern Science", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 10, page no. ppc584-c592, October-2025, Available at : http://www.jetir.org/papers/JETIR2510275.pdf