• Mayuri pravin gangurde
• Mayur Gaikar
• Vaishnavi madan kadam
• Apeksha santosh gholap
• Sayali Nilesh Kote

Wheatgrass (Triticum aestivum) and Catharanthus roseus (L.) G. Don is two medicinal plants widely recognized for their significant roles in cancer prevention and therapy. Wheatgrass juice is rich in bioactive compounds such as chlorophyll, flavonoids, vitamins, minerals, and enzymes that exhibit strong antioxidant, detoxifying, and immunomodulatory properties. Clinical and experimental studies have shown that wheatgrass juice can enhance immune function, increase levels of anti-inflammatory cytokines such as IL-10, and reduce chemotherapy-induced toxicities by maintaining white blood cell (WBC) counts. These effects suggest that wheatgrass acts as a potent supportive supplement during chemotherapy, improving the patient’s overall tolerance and recovery. On the other hand, Catharanthus roseus, commonly known as Madagascar periwinkle, is an important source of more than 130 alkaloids, among which vincristine and vinblastine are widely used in the treatment of various cancers, including leukemia, Hodgkin’s lymphoma, and breast cancer. These alkaloids interfere with cell division by binding to tubulin, thereby inhibiting mitosis in rapidly dividing cancer cells. Beyond its anticancer potential, C. roseus also exhibits antidiabetic, antimicrobial, and antioxidant activities. Modern biotechnological techniques such as tissue culture and metabolic engineering are being employed to enhance the yield of its valuable alkaloids for pharmaceutical applications. Together, wheatgrass juice and Catharanthus roseus demonstrate the powerful therapeutic potential of medicinal plants in cancer treatment—wheatgrass serving as an immune-supportive and detoxifying adjunct during chemotherapy, and C. roseus as a primary source of potent anticancer compounds. Their combined significance highlights the importance of integrating natural plant-based therapies with conventional medicine for improving cancer care and patient outcomes.

vincristine, vinblastine, anticancer activity, antioxidant, chemotherapy, alkaloids, immunomodulatory effects.

"A Review On Catharanthus And Wheatgrass Juice Used For Treatment Of Cancer", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 10, page no.c716-c733, October-2025, Available :http://www.jetir.org/papers/JETIR2510291.pdf

"A Review On Catharanthus And Wheatgrass Juice Used For Treatment Of Cancer", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 10, page no. ppc716-c733, October-2025, Available at : http://www.jetir.org/papers/JETIR2510291.pdf