• Mr. Sagar Babasaheb Mhaske
• Mr. Rajendra Lamkhede

Background of study: Liver failure is a critical medical condition marked by the liver's inability to function adequately, resulting in high morbidity and mortality rates. Globally, liver disease is responsible for 4% of all deaths, or about two million deaths annually. In India, liver disease deaths accounted for 2.95% of total deaths in 2017, or 259,749 deaths. It stems from various causes, including viral hepatitis, alcohol-related liver disease, autoimmune disorders, metabolic abnormalities, and drug-induced damage. Despite medical advancements, managing liver failure remains challenging, necessitating a deeper understanding of its clinical profile and treatment outcomes. This study aims to fill this gap by investigating the demographic characteristics, etiological factors, severity markers, and treatment responses in patients with liver failure. By analyzing real-world data on patient demographics, disease severity, laboratory findings, and treatment modalities, the study seeks to enhance our understanding of prognostic factors and therapeutic approaches. Ultimately, the findings could inform clinical decision-making, improve patient care strategies, and potentially lead to the development of more effective treatments for this life-threatening condition Objectives: 1. To assess the clinical profile and outcome of Liver failure patients 2. To compare outcome of Liver failure patients with their selected socio-demographic and clinical characteristics Material and methods: The overall plan addressing a research question including strategies for enhancing the study’s integrity.In this study Non-Experimental, descriptive study design with prospective cross-sectional approach was used. Setting is more specific places where data collection occurs. The physical location and condition in which the data collections take place in a study is terminal as the setting of the Study In this study Setting of the study was Pravara Rural Hospital, Loni.Results: The data presented in Table 4 and Figure 3 shows that, majority 35 (58.33%) of the respondents were had fatty liver failure and 25(41.66%) were had non fatty With respect to respondents number of days hospital stays/ treatment data presented in Table 4 and Figure 4 shows that, majority 25(41.66%) of the respondents were stay in hospital 0-1 months, 20(33.33%) of respondents werestay in hospital 1 month to 1 year & 15 (25%) of respondents werestay in hospita 1 to 5 year. With respect to Severity of Liver Failure of respondents, Table 4 and Figure 6 shows that, majority 47(78.33%) of respondents were had acute liver failure, 13(21.66%) of respondents were hadchronic liver failure..

Liver failure, clinical profile, outcome, acute liver failure, NAFLD, alcohol, rural healthcare, India.

"Clinical Profile and outcome of Liver Failure patients admitted at Pravara Rural Hospital Loni (BK)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 10, page no.d634-d638, October-2025, Available :http://www.jetir.org/papers/JETIR2510382.pdf

"Clinical Profile and outcome of Liver Failure patients admitted at Pravara Rural Hospital Loni (BK)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 10, page no. ppd634-d638, October-2025, Available at : http://www.jetir.org/papers/JETIR2510382.pdf