• DR RITIKA NAGPAL
• DR SATRUGHNA BEHERA
• DR ANIKET RAJPUT
• DR DEEPAK KUMAR

Vatarakta is a well-described Vata-Rakta disorder in Ayurvedic classics, closely resembling gout in its metabolic and inflammatory manifestations. It arises from Rakta Dushti and Avarana of Vata, resulting in pain, swelling, and discolouration of joints. Among the five major Shodhana Karmas, Virechana is specifically indicated for Pitta-Rakta predominant conditions such as Vatarakta, offering systemic detoxification and correction of metabolic derangements. This review explores the Ayurvedic and pharmacological rationale behind some classical formulations employed in Virechana Karma for Vatarakta, namely Patoladi Kwatha ( Deepana Pachana ), Kalyanaka Ghrita (Snehapana), Trivrit Avaleha (Virechana), and Triphala Kwatha (Anupana). Each formulation is discussed with respect to its classical references, Rasa–Guna–Virya–Vipaka–Karma, and therapeutic relevance in Vatarakta. The review emphasizes the pharmacodynamic rationale and clinical utility of these preparations, which act synergistically to pacify Vata–Pitta, purify Rakta, and restore Agni. Correlation with modern pharmacology highlights their anti-inflammatory, hepatoprotective, hypouricemic, and antioxidant activities. This integrative perspective demonstrates how the classical Ayurvedic approach to Virechana offers a scientifically coherent method for managing metabolic and inflammatory arthropathies such as gout.

Patoladi kwath, Kalyanak ghrita, Trivrit Avaleha, Triphala kwath, Gout

"Pharmacological Rationale of Ayurvedic Formulations Used in Virechana Karma for Vatarakta: A Comprehensive Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.12, Issue 11, page no.c763-c772, November-2025, Available :http://www.jetir.org/papers/JETIR2511292.pdf

"Pharmacological Rationale of Ayurvedic Formulations Used in Virechana Karma for Vatarakta: A Comprehensive Review ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.12, Issue 11, page no. ppc763-c772, November-2025, Available at : http://www.jetir.org/papers/JETIR2511292.pdf