• Surendra Singh Gurjar
• Brahm Dutt Sharma
• Nisha Ojha

Background: Iron Deficiency Anaemia (IDA) remains a major public health problem in children, particularly in developing countries. Although conventional iron supplementation is effective, long-term use is frequently associated with gastrointestinal intolerance and poor compliance. Ayurvedic herbomineral formulations have been traditionally used for anemia, but concerns regarding safety, especially in pediatric populations, necessitate systematic evaluation. Objectives: To critically evaluate the clinical safety of commonly used Ayurvedic iron formulations in the management of childhood IDA. Methods: A narrative review of clinical trials, observational studies, experimental toxicological studies, and pharmacovigilance reports was conducted. Pediatric studies evaluating safety outcomes such as adverse drug reactions, liver and renal function tests, and hematological parameters were prioritized. Classical Ayurvedic formulations including Mandura Bhasma, Loha Bhasma, Dhatri Lauha, and Trikatrayadi Lauha were included. Results: The majority of reviewed clinical studies demonstrated significant improvement in hemoglobin concentration and red blood cell indices with minimal adverse effects. Reported adverse events were mild, self-limiting, and did not necessitate treatment discontinuation. Biochemical safety parameters remained within normal limits. Experimental studies further supported the safety of these formulations when prepared using classical standardized methods. Discussion & Conclusion: Ayurvedic iron formulations appear to be clinically safe and well tolerated in children with IDA when administered in appropriate doses under professional supervision. These formulations may serve as a viable alternative or adjunct to conventional iron therapy, provided strict quality control and pharmacovigilance measures are ensured.

Iron Deficiency Anaemia; Pediatric Anemia; Mandura Bhasma; Loha Bhasma; Ayurvedic Safety

"Clinical Safety Analysis of Ayurveda-Derived Therapies for Iron Deficiency Anemia in Children: A narrative review.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 1, page no.a820-a827, January-2026, Available :http://www.jetir.org/papers/JETIR2601096.pdf

"Clinical Safety Analysis of Ayurveda-Derived Therapies for Iron Deficiency Anemia in Children: A narrative review.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 1, page no. ppa820-a827, January-2026, Available at : http://www.jetir.org/papers/JETIR2601096.pdf