• Dukare kalyani balnath
• Dr. Kiran B dhamak
• Monali balasaheb shelke

The rise of three-dimensional (3D) printing represents an exciting advancement within the pharmaceutical sector, enabling enhanced levels of accuracy, adaptability, and customization during medication production. This innovation allows for the development of intricate medication delivery systems featuring precisely timed releases and customized dosages suited specifically to each patient's medical requirements. Following the FDA authorization of Spritam®, there is an increasing focus on utilizing additive manufacturing techniques to create personalized medications and innovative therapeutic formulations. Using sophisticated methods like fused deposition modeling (FDM), semi-solid extrusion (SSE), stereolithography (SLA), and binder jetting, three-dimensional printers enable the creation of various tablets, encompassing immediate-, sustained-, delayed- and pulse-releasing varieties. With these technological tools, pharmacological researchers can meticulously construct molecular architectures affecting drug release speeds, absorption levels, and overall treatment effectiveness. Additionally, 3D printing facilitates quick model creation, cutting down on both timelines and expenses during pharmaceutical research without hindering personalized manufacturing for individual patients. Nevertheless, significant hurdles remain for broad industry acceptance of this tech. Major obstacles encompass insufficient access to appropriate bio-compatible substances, absence of standardized procedures, substantial expenses for machinery, sluggish manufacturing rates, and intricate legal requirements. Furthermore, sustaining uniformity in products along with ensuring high-quality control throughout production runs is still an important issue. Although there are current constraints, 3D printing demonstrates considerable potential in advancing personalized healthcare strategies. As material sciences, AI, and pharmacogenomics continue to evolve, they anticipate playing an indispensable part in shaping future pharmaceutical production methods – revolutionizing how drugs are developed, manufactured, and distributed globally among patients.

Three-dimensional (3D) printing , Drug delivery systems , Fused Deposition Modeling (FDM) , Semi-Solid Extrusion (SSE) , Personalized medicine , Controlled drug release , Pharmaceutical formulation.

"3D printing in tablet dosage form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 1, page no.b31-b45, January-2026, Available :http://www.jetir.org/papers/JETIR2601106.pdf

"3D printing in tablet dosage form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 1, page no. ppb31-b45, January-2026, Available at : http://www.jetir.org/papers/JETIR2601106.pdf