• Dr Gitika P Patil
• Dr Sudhir L Tungikar
• Dr Pranav Kothari

Title: Assessment of Lipoprotein(a) Levels Among Acute Myocardial Infarction (AMI) Patients Author: Dr. Gitika Pratap Patil Co-author: Dr Sudhir L Tungikar Dr Pranav Kothari Details of participation :JR 2-General Medicine Institute details : Pravara institute of medical sciences,Loni Introduction: Myocardial infarction (MI) is an emerging public health concern, with rising incidence linked to both lifestyle and genetic factors. Lipoprotein(a) [Lp(a)], a genetically determined lipid particle, is now recognized as a significant, independent risk factor for atherosclerotic cardiovascular disease and MI, affecting about 20% globally. Despite its strong association with premature MI, effective Lp(a)-lowering therapies are lacking, and guidelines remain unclear. Duration of study: one year Objective: ·  To determine the distribution and mean levels of Lp(a) among AMI cases.  ·  To analyze the correlation between elevated Lp(a) levels and clinical severity or type of AMI.   Material and methods: This 1-year prospective study was conducted in the Department of Medicine with 50 participants. After obtaining informed consent, data were collected through medical history, clinical examination, ECG, 2D Echo, cardiac enzymes, coronary angiography, and laboratory investigations including lipid profile and serum Lp(a) levels. The aim was to aassess the serum levels of Lipoprotein(a) [Lp(a)] in patients diagnosed with acute myocardial infarction. Data analysis was performed using SPSS and OpenEpi, with statistical significance set at p < 0.05. Chi-square and t-tests were applied for categorical and continuous variables, respectively. Results and observation Thus total 50 cases having acute myocardial infarction were studied and following results were observed. The mean age was 54.5 years and predominance of males was seen. They had higher BMI and a more atherogenic lipid profile—elevated LDL, triglycerides, fasting blood sugar, and lower HDL. Mean LPa was 53.7 mg/dL. Lp(a) levels >50 mg/dL were strongly associated with CAD. ST changes and infarctions varied in location, and 43% had LVEF <40%. Discussion Study by Vandana Saini et al 54 showed that mean age among cases was 59.4 and mean LPa among cases was 51.4 and Mean LPa in present study was 53.7 mg/dL. Study by Mehdi Afshar et al 52 showed that mean age was 49 years. Conclusion Elevated Lp(a) was identified as a raised for AMI cases, frequently overlooked in standard lipid profiles. Early screening can help detect high-risk individuals and improve prevention, particularly among young Indians.

"Assessment of Lipoprotein(a) levels among acute myocardial infarction (AMI) patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 1, page no.b261-b266, January-2026, Available :http://www.jetir.org/papers/JETIR2601142.pdf

"Assessment of Lipoprotein(a) levels among acute myocardial infarction (AMI) patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 1, page no. ppb261-b266, January-2026, Available at : http://www.jetir.org/papers/JETIR2601142.pdf