• Dr Pawar Sankirna Appu
• Dr Sumarani Rajesh

Introduction - Polycystic Ovarian Disease (PCOD) is a multifactorial endocrine disorder affecting women in their reproductive years and is one of the leading causes of menstrual irregularities and infertility. Where modern medicine attributes PCOD to hormonal imbalance, insulin resistance, and ovarian dysfunction providing only symptomatic relief,Ayurveda can be beneficial as an holistic approach in treating the condition of PCOD with minimal side effects provided by modern medicines in long term usage. In Ayurveda, PCOD can be correlated with Artavakshaya, Vandhyatva, and Pushpaghni Jataharini, where Kapha-Vata Dosha predominance leads to obstruction of Artavavaha Srotas. Improper lifestyle, sedentary habits, and Agnimandya further aggravate the condition. Nasya Karma, the administration of medicated substances through the nasal route, is considered the most effective therapy for disorders related to the Urdhvajatrugata region. Since the nose is described as the “Dwara of Shiras”, Nasya directly influences the central nervous system and endocrine pathways, thereby helping in hormonal regulation. Shigru Beejadi Ghrita possesses Tikshna, Ushna, Kapha-Vatahara, and Srotoshodhana properties, while MD Fort Taila is known for its Balya, Vata-shamaka, and neuro-endocrine stabilizing effects. Hence, the present study was undertaken to evaluate their role in anovulation in PCOD management. Material and Methods: An open-label, randomized, comparative clinical study was conducted on 40 patients diagnosed with Polycystic Ovarian Disease (PCOD), selected from the OPD/IPD after obtaining informed consent. Patients aged 21–35 years with clinical and ultrasonographic features of PCOD and menstrual irregularities were included, while pregnant or lactating women and those with other endocrine or structural uterine disorders were excluded. The patients were randomly divided into two groups of 20 each. Group A received Nasya Karma with Shigru Beejadi Ghrita and Group B with MD Fort Taila. Nasya was administered in a dose of 2 bindus (1 ml) in each nostril once daily for 10 consecutive days in each menstrual cycle for three consecutive cycles. Prior to Nasya, local Abhyanga of the face and neck followed by Swedana was performed. The respective Ghrita or Taila was instilled in the supine position during Pradhana Karma, followed by Paschat Karma including Gandusha with Ushna jala. Clinical assessment was carried out before and after treatment based on menstrual regularity, cycle duration, and associated symptoms such as acne, weight gain, and hirsutism. The data obtained were statistically analyzed to assess the efficacy of the interventions. Discussion: Nasya Karma acts through the Nasa-Shira-Marga and influences the hypothalamic-pituitary-ovarian axis, thereby regulating hormonal imbalance. Shigru Beejadi Ghrita, with its Tikshna and Kapha-Vatahara properties, helps in clearing Srotorodha and improving Agni, facilitating normal ovarian function. MD Fort Taila, owing to its Balya and Vata-shamaka properties, supports neuro-endocrine coordination and stabilizes menstrual cyclicity. Thus, Nasya Karma with both formulations effectively achieves Samprapti-Vighatana in PCOD. Results: Statistical analysis of the data revealed significant improvement in clinical parameters in both treatment groups after completion of therapy. In Group A (Shigru Beejadi Ghrita Nasya), follicular growth and endometrial thickness showed statistically significant improvement (p < 0.05), along with reduction in cycle irregularity and associated symptoms. Group B (MD Fort Taila Nasya) also demonstrated statistically significant improvement (p < 0.05) in follicular growth and endometrial thickness along with menstrual cyclicity . Inter group comparison showed comparable efficacy of both interventions, with no statistically significant difference between the groups (p > 0.05). No adverse drug reactions were observed during the study, indicating that both Nasya therapies were safe and well tolerated

Polycystic Ovarian Disease, Nasya Karma, Shigru Beejadi Ghrita, MD Fort Taila, Artavavaha Srotas, Hormonal Imbalance

"“RANDOMISED CLINICAL TRIAL TO EVALUATE THE EFFICACY OF SHIGRU BEEJADI GHRUTA AND M D FORTE TAILA NASYA IN THE MANAGEMENT OF ANOVULATION IN POLYCYSTIC OVARIAN DISEASE (PCOD)’’", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 1, page no.c618-c633, January-2026, Available :http://www.jetir.org/papers/JETIR2601274.pdf

"“RANDOMISED CLINICAL TRIAL TO EVALUATE THE EFFICACY OF SHIGRU BEEJADI GHRUTA AND M D FORTE TAILA NASYA IN THE MANAGEMENT OF ANOVULATION IN POLYCYSTIC OVARIAN DISEASE (PCOD)’’", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 1, page no. ppc618-c633, January-2026, Available at : http://www.jetir.org/papers/JETIR2601274.pdf