• Dr. Kiran Kapadia
• Dr. Sheetal Mirajkar

Rubia cordifolia linn. commonly known as Manjishtha is an important medicinal plant widely used in Ayurveda, Unani and Traditional Chinese. Manjishtha is the magic drug, which is described in all the textbook of Ayurvedic science including Brihattrayi, Laghuttrayi, and Nighantus. The description of the Manjishtha for its Ayurvedic yogas and its therapeutic utilization are varied and described to cure various diseases. Manjishtha its traditional use blood detoxification, skin health, wound healing and metabolic regulation. Current laboratory and experimental research shows that it gives significant result in cancer. However, there is need to further investigation along with clinical research. In Manjishtha, over 100 bioactive compounds predominantly occurring in roots and rhizomes. These mainly include anthraquinones (eg.purpurin, alizarin, manjistin), naphthoquinone, bicyclichexapeptides,triterpenoids,flavonoids,phenol,acids,iridoids,polysaccharides,alkalois,tannins,and glycosides. Anthraquinones and related quinone derivative responsible for many biological activities These include antioxidant, anti-inflammatory, antimicrobial, anticancer, immunomodulator nephro protective, hepatoprotective, anti-platelet aggregation, cardioprotective effect observe in preclinical models. Flavonoids, tannins, phenol and saponins have antioxidant and antimicrobial properties. Despite extensive phytochemical characterization, clinical evidence remains limited. Gaps in pharmacokinetic safety and clinical research highlight need for well designed human trial to validate safe clinical use.

Manjishtha, Rubia cordifolia, phytochemical, anthraquinones, traditional medicine.

"A Comprehensive Drug Review of Manjishtha (Rubia Cordifolia)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 3, page no.d413-d424, March-2026, Available :http://www.jetir.org/papers/JETIR2603349.pdf

"A Comprehensive Drug Review of Manjishtha (Rubia Cordifolia)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 3, page no. ppd413-d424, March-2026, Available at : http://www.jetir.org/papers/JETIR2603349.pdf