• Tejas Ghagre
• Bhupendra Tiwari
• Himanshu Sarkar
• Anjali Yadav
• Dr. Vaishali Rathi

A nanoemulsion serum co-loaded with Vitamin C and E was formulated and evaluated for topical application. The nanoemulsion showed promising results in terms of stability (up to 3 months), particle size (100-200 nm), entrapment efficiency (80-90%), and antioxidant activity (70-80% DPPH scavenging). The formulation has potential for improved bioavailability and stability of vitamins, making it a promising candidate for skin care applications. Further studies are needed to optimize and evaluate its efficacy in vivo. The Vitamin C and E co-loaded nanoemulsion serum formulation showed promising results in terms of stability, particle size, and antioxidant activity. The average particle size of the nanoemulsion was found to be around 100-200 nm, indicating a stable and uniform dispersion. The entrapment efficiency of Vitamin C and E was found to be around 80-90%, indicating effective loading of the vitamins. The nanoemulsion serum showed significant antioxidant activity, with a DPPH scavenging activity of around 70-80%. The nanoemulsion serum was found to be stable at room temperature (25°C) and refrigerated conditions (4°C) for up to 3 months. The results suggest that the developed nanoemulsion serum has potential for topical application, with improved stability and bioavailability of Vitamin C and E.

Antioxidants, Nanoemulsions, Comprehensive, Dispersion, Aesthetic

"FORMULATION AND EVALUATION OF VITAMIN C&E COLOADED NANOEMULSION SERUM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 3, page no.e510-e521, March-2026, Available :http://www.jetir.org/papers/JETIR2603460.pdf

"FORMULATION AND EVALUATION OF VITAMIN C&E COLOADED NANOEMULSION SERUM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 3, page no. ppe510-e521, March-2026, Available at : http://www.jetir.org/papers/JETIR2603460.pdf