• Dharmendra Singh Gusain
• vikas Narwariya
• Neha Sarna
• Dheeraj Nautiyal

Abstract Background: Uric acid (UA) is the final enzymatic product of purine metabolism in humans and is regulated by the xanthine-oxidoreductase enzyme. Serum uric acid (SUA) levels are influenced by purine metabolism, dietary intake, endogenous synthesis, and renal excretion. Recent evidence suggests a possible association between elevated uric acid levels and abnormalities in glucose metabolism, including prediabetes and diabetes mellitus. Objectives: To categorize healthy, prediabetic, and diabetic individuals based on fasting blood glucose (FBG) and HbA1c levels; to measure serum uric acid and blood glucose levels among these groups; and to evaluate the relationship between serum uric acid and glucose levels. Methods: This observational study included adults aged above 20 years. Demographic data (age, gender), clinical variables (duration of diabetes, family history, smoking status), and anthropometric measurements (height, weight, BMI, waist-hip ratio) were collected. Biochemical parameters such as fasting blood sugar (FBS), random blood sugar (RBS), HbA1c, serum urea, creatinine, and uric acid were analyzed. Statistical analysis was performed using SPSS version 22.0. Results: Descriptive statistics of biochemical and demographic variables were analyzed. Significant correlations were observed between serum uric acid levels and FBS, RBS, overall blood glucose, and HbA1c levels across healthy, prediabetic, and diabetic groups. Conclusion: The study demonstrates a positive association between increasing serum uric acid levels and rising glucose levels, suggesting that uric acid may serve as a potential biomarker in the monitoring and management of diabetes mellitus.

Uric acid, Glucose, FBS, RBS, HbA1c

"Association between Serum Uric Acid and Glycemic Status in Healthy, Prediabetic, and Diabetic Individuals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 3, page no.g42-g57, March-2026, Available :http://www.jetir.org/papers/JETIR2603605.pdf

"Association between Serum Uric Acid and Glycemic Status in Healthy, Prediabetic, and Diabetic Individuals", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 3, page no. ppg42-g57, March-2026, Available at : http://www.jetir.org/papers/JETIR2603605.pdf