Abstract
Blood pressure regulation is a complex physiological process involving coordinated cardiac, vascular, neural, and hormonal mechanisms. Ayurveda describes Vata Dosha as the principal regulator of various physiological activities and classifies it into five subtypes, among which Prana Vayu and Vyana Vayu have important roles in cardiovascular regulation. Prana Vayu, primarily located in Murdha and associated with Hridaya functions, may be conceptually correlated with neural regulation of cardiac activity, including modulation of heart rate and cardiac rhythm. Vyana Vayu, with Hridaya as one of its principal sites, is responsible for the circulation and distribution of Rasa and Rakta throughout the body and may be correlated with peripheral circulation, vascular tone, venous return, and tissue perfusion.
The present review explores the role of Prana and Vyana Vayu in the regulation of blood pressure and examines their possible correlation with contemporary physiological mechanisms. The functions of the medullary cardiovascular centres, autonomic nervous system, baroreceptor and chemoreceptor mechanisms, and Renin–Angiotensin–Aldosterone System are considered in relation to the Ayurvedic concepts of Prana and Vyana Vayu. The review also discusses the Ayurvedic understanding of hypertension and the importance of maintaining harmony between Prana and Vyana Vayu.
Management of hypertension is discussed through an integrated Ayurvedic approach involving appropriate Ahara and Vihara, lifestyle modification, Yoga, Pranayama, aerobic exercise, selected Ayurvedic medications, and appropriate Panchakarma procedures. Nasya Chikitsa may also have relevance in maintaining the functions of Prana Vayu. The review emphasizes the importance of considering Prana, Vyana, Apana Vayu, Agni, Rasa, Rakta, and Medo Dhatu in understanding blood pressure regulation from an Ayurvedic perspective. An integrative interpretation of Ayurvedic principles through contemporary physiological concepts may help strengthen their understanding and facilitate their appropriate application in clinical practice.