• Ms. Sadhana Kailas Rode
• Mrs. Sandnya Gawade

Abstract Background of study: Medicine are widely used to treat, prevent, and manage a broad range of health condition while therapeutic interventions are intended to promote health, they may also produce unwanted or harmful effect known as adverse Adverse drug reactions (ADRs) are unexpected and unplanned reactions to drugs, even though normal doses are being used. Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality. It has been estimated that around 2.9-5.6% of all hospital admissions are due to ADRs and as many as 35% of hospitalized patients experience an ADR during their hospitalization. Fatal ADRs rank among the most common causes of death in the United States. The economic burden of ADRs is also considerable; for example in the United States, annual total cost of $47.4 billion for 8.7 million drug related admissions were reported. ADR spontaneous reporting systems may detect previously unrecognized adverse reactions and identify risk factors that predispose to drug toxicity and investigate causality. Spontaneous reporting of ADRs has remained the cornerstone of pharmacovigilance and is important in maintaining patient safety. However, reporting of serious ADRs rarely exceeds 10%. The initiative of an international reporting system for ADRs came in the wake of the thalidomide tragedy in the early 1960s. Voluntary ADR reporting schemes have operated since the early 1960s in many western countries, first one started in the United Kingdom in 1964. According to the World Health Organization standards, countries with the best reporting rates generate over 200 reports per 1,000,000 inhabitants per year. Therefore, in Iran with a population over 60 million, it is expected to receive at least 12000 reports per year. Unfortunately, only 2330 reports were sent to the IPC in 2006. The reporting of ADRs in hospitals is very important because severe ADRs are most likely to be seen in hospitals, ADRs can be detected early and spontaneous reports can be more accurate. Material and Methods: A pre-experimental one-group pre-test and post-test research design was used to assess the effectiveness of a nurse-led education programme on knowledge regarding adverse drug reactions (ADRs) among the general population in a selected village of Rahata Taluka. The study sample comprised 60 participants from the general population of the selected village. A non-probability convenience sampling technique was employed for sample selection. Knowledge regarding adverse drug reactions was assessed before and after the implementation of the nurse-led education programme using a structured questionnaire. The collected data were analyzed using descriptive and inferential statistics, including mean, mean difference, paired t-test, and chi-square test. Result: The demographic finding suggests that majority of general population, 23 (38.33%), belonged to the 19–38 years age group, majority gender 35 (58.33%) were female and 25 (41.66%) were male. In terms of educational qualification, the largest proportion of the general population, 22 (36.66%), had completed primary education, whereas only 3 (5%) respondents were graduates or had attained higher educational qualifications. Regarding occupation, the majority of respondents, 18 (30%), were housewives. Analysis of monthly family income showed that 24 (40%) respondents had a monthly family income of less than ₹10,000, whereas only 6 (10%) reported a monthly family income above ₹30,000. With respect to the frequency of medicine use, the majority of respondents, 49 (81.66%), reported that they frequently used medicines, while 11 (18.33%) stated that they did not use medicines frequently. Concerning experience of side effects from medicines, a substantial proportion of respondents, 42 (70%), reported having experienced side effects from medications at some point, whereas 18 (30%) had never experienced any side effect.In the pre-test level of knowledge of majority of general population 26 (43.33%) were having inadequate knowledge, 29 (48.33%) had moderately adequate knowledge, and only 5 (8.33%) had adequate knowledge. The mean pre-test score was 8.46. whereas in the post-test level of knowledge majority of general population with inadequate knowledge decreased to 8 (13.33%), while those with moderately adequate knowledge increased to 33 (55%). The number of general population with adequate knowledge increased substantially to 19 (31.66%). The mean post-test score was 13.7. The mean difference was found of pre-test score was 4.47 and post- test score was 4.64 with the standard deviation of mean difference was found out to be 5.24. The calculated ‘t’ value was found to be 5.60 with ‘p’ value 0.001* which is significant concluding that the nurse led education program was found to be effective in improving level of knowledge regarding adverse drug reaction among the general population in a selected village of Rahata Taluka. There was no any significant association between post-test knowledge regarding adverse drug reactions and the selected demographic variables among the general population in a selected village of Rahata Taluka. However, a significant association was found with the participants experience of side effects from medicines. Conclusion: The study findings have shown that the nurse led-education programme was effective to enhance level of knowledge regarding adverse drug reaction among the general population in a selected village of Rahata Taluka.

"“A study to assess the effectiveness of nurse led education program on knowledge regarding adverse drug reaction among general population in a selected village of Rahata Taluka.”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 9, page no.c363-c370, September-2026, Available :http://www.jetir.org/papers/JETIR2609239.pdf

"“A study to assess the effectiveness of nurse led education program on knowledge regarding adverse drug reaction among general population in a selected village of Rahata Taluka.”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 9, page no. ppc363-c370, September-2026, Available at : http://www.jetir.org/papers/JETIR2609239.pdf