• Usha S Wasnik

Abstract The present study investigates the acoustic and thermodynamic properties of Vadadustat in selected solvent media at 300K to understand drug–solvent molecular interactions. Ultrasonic velocity, density and viscosity measurements will be carried out at different concentrations of Vadadustat. Various acoustic and thermodynamic parameters, including adiabatic compressibility, intermolecular free length, acoustic impedance, apparent molar volume, apparent molar compressibility, relative association and excess properties, will be evaluated from the experimental data. The concentration dependence of these parameters will be analysed to elucidate solute–solvent and solvent–solvent interactions, particularly hydrogen bonding and structural effects. The study is expected to provide useful insights into the solution-state behaviour and physicochemical characteristics of Vadadustat and demonstrate the utility of ultrasonic techniques for investigating molecular interactions in pharmaceutical systems. Keywords: Vadadustat; ultrasonic velocity, acoustic properties, thermodynamic properties, molecular interactions, hydrogen bonding

Vadadustat; ultrasonic velocity, acoustic properties, thermodynamic properties, molecular interactions, hydrogen bonding

"Experimental Investigation of Acoustic Properties and Molecular Interactions of Vadadustat in Aqueous–Organic Solvent Mixtures at 300 K", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.13, Issue 10, page no.b853-b858, October-2026, Available :http://www.jetir.org/papers/JETIR2610189.pdf

"Experimental Investigation of Acoustic Properties and Molecular Interactions of Vadadustat in Aqueous–Organic Solvent Mixtures at 300 K", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.13, Issue 10, page no. ppb853-b858, October-2026, Available at : http://www.jetir.org/papers/JETIR2610189.pdf