• Dr. S.D.K. SHRI DEVI

The aim of the present investigation was to evaluate the anti-cancer potential of red seaweeds namely Ahnfeltiopsis densa (J.Ag.) Silva et Decew, Hypnea flagelliformis Greville ex J.Ag. and Laurencia papillosa (Forssakal) Greville collected from Hare Island (Thoothukudi district), Koothankuzhi (Tirunelveli district) and Kanyakumari (Kanyakumari district) respectively in the south east coast of Tamil Nadu, India for the inhibitory effect against A-549 cell line. The viability percentage of the cell lines were carried out by using Trypan blue dye exclusion method and the cytotoxicity. The methanolic extract of the selected seaweeds has significant cytotoxicity effect on A-549 cell line. Among the three seaweeds studied, Ahnfeltiopsis densa (J.Ag.) Silva et Decew showed more effect, followed by Hypnea flagelliformis Greville ex J.Ag. and Laurencia papillosa (Forssakal) Greville in the concentration range between 25 to 200µg/ml of methanolic extract by using MTT assay. From the performed assay, it was noted that methanolic extract of the selected red seaweeds show greater activity on A-549 cell line which can be used as anti-cancer activity.

Anti-cancer, A-549 cell line, Methanolic extract, Red seaweeds, Tamil Nadu, India

" ANTI-CANCER POTENTIAL OF THE SELECTED RED SEAWEEDS COLLECTED FROM THE SOUTH EAST COAST OF TAMIL NADU, INDIA ON A549 CELL LINE.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.220-223, March-2019, Available :http://www.jetir.org/papers/JETIRAD06034.pdf

" ANTI-CANCER POTENTIAL OF THE SELECTED RED SEAWEEDS COLLECTED FROM THE SOUTH EAST COAST OF TAMIL NADU, INDIA ON A549 CELL LINE.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp220-223, March-2019, Available at : http://www.jetir.org/papers/JETIRAD06034.pdf