• A.Nirmala
• G.Manimekalai

The plants have been used traditionally for centuries and modern scientific studies have shown the existence of good correlation between the traditional or folkloric application of some of the plants further strengthens the search for pharmacological active components from plants. As a very common chronic disease, diabetes is becoming the third “Killer” of the health of mankind along with cancer, cardiovascular and cerebrovascular diseases because of its high prevalence, morbidity and mortality. Therefore once diagnosed, it is well regulated by means of various therapeutically effective drugs. Besides, the therapy based on chemotherapeutic agents, the present century has progressed towards naturopathy. Thus, medicinal plants have an ever emerging role to play in treatment or management of lifelong prolonging diseases like diabetes mellitus, especially in developing countries. Diabetes mellitus alone is accompanied with several other diseases infecting healthy individuals. The treatment of each of such disease can be done by exploiting the herbal integrity of India. The plants in parts or as full can be used for curing any disorder related with diabetes mellitus. Moreover, in some cases extracts of plants are self-capable of treating the related disorders such as polyuria, polydipsia, glucosuria, etc., along with curing the chronic disorders such as diabetes mellitus.. In the present study, the hydroalcoholic extract of Aegle marmelos was used to study the antidiabetic activity in streptozotocin-induced diabetic rats and compared to standard glibenclamide. The results obtained showed that the 400 mg/kg Aegle marmelos extract had better antidiabetic activity which could be because of either increase in utilization of glucose or by direct stimulation of glucose uptake through increased insulin secretion. Thus, it can be inferred that the plant Aegle marmelos has potent antidiabetic activity.

Aegle marmelos, streptozotocin, glibenclamide ,Medicinal plant

"ANTIDIABETIC ACTIVITY OF THE AEGLE MARMELOS FRUIT EXTRACTS USING WISTER RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.281-288, March-2019, Available :http://www.jetir.org/papers/JETIRAD06047.pdf

"ANTIDIABETIC ACTIVITY OF THE AEGLE MARMELOS FRUIT EXTRACTS USING WISTER RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp281-288, March-2019, Available at : http://www.jetir.org/papers/JETIRAD06047.pdf