• Dr.S.Menaga

Cancer is the third leading cause of death worldwide , claiming over 6 million lives every year preceded by cardiovascular and infectious diseases. Plants have a long history of use in the treatment of cancer. Drug discovery from plants is a multi – disciplinary approach which combines various botanical, ethnobotanical, phytochemical, biological and chemical separation techniques. Over 50% of the drugs in clinical trials for antitumor activity were isolated from natural source. The assessment of the cytotoxicity of ethanol extract of Pentatropis capensis was based on the data from MTT assay. Our present study observed that the ethanol extract of Pentatropis capensis inhibited the proliferation of human cell line(HeLa). From the results obtained, it is apparent that the extract from Pentatropis capensis was active in inhibiting in vitro cell proliferation. The number of colonies decreased significantly in a concentration dependent manner, suggesting that Pentatropis capensis suppressed the regeneration potential of cancer cells in higher concentrations.

Pentatropis capensis, cisplatin, hela cell lines, MTT assay.

"INVITRO ANTICANCER ACTIVITY OF ETHANOLIC EXTRACT OF PENTATROPIS CAPENSIS (L.f.) Bullock AGAINST HeLa CELL LINES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.408-413, March-2019, Available :http://www.jetir.org/papers/JETIRAD06066.pdf

"INVITRO ANTICANCER ACTIVITY OF ETHANOLIC EXTRACT OF PENTATROPIS CAPENSIS (L.f.) Bullock AGAINST HeLa CELL LINES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp408-413, March-2019, Available at : http://www.jetir.org/papers/JETIRAD06066.pdf