• Jayashri D. Bhirud
• Hemant P. Narkhede

We report herein synthesis of substituted (thiazol-2-yl)diazenyl) derivatives in two steps. Initially diazotization of 2-aminothiazole was takes place in presences of sodium nitrite, then this diazotized product undergo coupling reaction with substituted aromatic compounds, yield azo dyes in good yield. We increased the yield by adjusting the pH to 7-8 by addition of base. The synthesized dyes were characterized by IR and 1H-NMR spectral analysis. The UV-visible study shows effects of solvent polarity on the maximum absorption wavelength. The results shows that most of the dyes showed positive solvatochromism, when the solvent is changed to a more polar solvents.All synthesized dyes were screened for their antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus and Salmonella typhi by well diffusion method.Some synthesized dyes shows good antibacterial activity. The synthesized dyes were found to give various shades of red.

Azo dyes, coupling reaction, diazotization, solvatochromism.

" Synthesis of (thiazol-2-yl)diazenyl) derivatives from 2-amino thiazole and their solvatochromism study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 3, page no.218-223, March-2019, Available :http://www.jetir.org/papers/JETIRAO06034.pdf

" Synthesis of (thiazol-2-yl)diazenyl) derivatives from 2-amino thiazole and their solvatochromism study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 3, page no. pp218-223, March-2019, Available at : http://www.jetir.org/papers/JETIRAO06034.pdf