• Sathishkumar R.
• Meghaa K.

Bacterial infections are common among many medical complications and one such type is erythrasma, which affects the folds of the skin (intertriginous area). This chronic superficial infection was caused by the organism Corynebacterium minutissimum. The lesion initially appears to be pink, as it progresses quickly and becomes brown and scaly. The aim of the present study is to identify drugs from plant sources, specifically against tetrahydrodipicolinate N-succinyltransferase (DapD) protein involved in the biosynthesis of L-lysine (PDB ID: 53ER). The secondary metabolites from the medicinal plant Prunus persica was selected and analysed in the present study. The phytocompounds reported in the literature for its presence were retrieved from PubChem database and the docking studies were carried out to observe the binding efficiency with the target protein. Among the compounds, chlorogenic acid had the G-Score of -7.56 kcal/mol and interactions were observed with Ser-325, His-185, Lys-207 and Asp-322. The future perspective of the study is to evaluate the antibacterial efficiency of the plant extracts against C. Minutissimum through in vitro techniques.

Erythrasma, Corynebacterium minutissimum, Tetrahydrodipicolinate N-Succinyltransferase, Prunus persica, Molecular docking studies, Chlorogenic acid.

"IN SILICO EVALUATION OF EFFICIENCY OF COMPOUNDS FROM THE MEDICINAL PLANT PRUNUS PERSICA AGAINST ERYTHRASMA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.7-10, May-2019, Available :http://www.jetir.org/papers/JETIRBK06002.pdf

"IN SILICO EVALUATION OF EFFICIENCY OF COMPOUNDS FROM THE MEDICINAL PLANT PRUNUS PERSICA AGAINST ERYTHRASMA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp7-10, May-2019, Available at : http://www.jetir.org/papers/JETIRBK06002.pdf