• Shreelakshmidevi Singaravelu
• Jaikumar S

The role of antioxidants in preventing oxygen radical and hydrogen peroxide induced cytotoxicity and tissue damage in various human diseases is becoming increasingly recognized. Lenalidomide a derivative of thalidomide possesses anti-neoplastic, immunomodulatory and antiangiogenic properties. Oxidative enzyme studies estimated in the breast tissue showed an increase in enzyme levels especially catalase in group III while the other enzymes were found to be elevated in group IV. Low levels of oxidative enzyme in group I indicate severe enzyme depletion and tissue destruction which was further substantiated by histopathological studies. Oxidative enzyme in erythrocyte lysate in drug treated group II & III were lower than normal levels.

"ANTI-OXIDANT EFFECT OF LENALIDOMIDE IN EXPERIMENTALLY INDUCED BREAST CANCER ON FEMALE WISTAR RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 5, page no.486-491, May-2019, Available :http://www.jetir.org/papers/JETIRCJ06105.pdf

"ANTI-OXIDANT EFFECT OF LENALIDOMIDE IN EXPERIMENTALLY INDUCED BREAST CANCER ON FEMALE WISTAR RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 5, page no. pp486-491, May-2019, Available at : http://www.jetir.org/papers/JETIRCJ06105.pdf