Abstract
Cissus quadrangularis Linn. is a medicinal plant belonging to family Vitaceae. The plant is probably native to India and Srilanka, but also found in Africa, Arabia and South East Asia. In India the plant is reported from Bihar, Odessa, West Bengal, Assam, Maharashtra, Goa, Andhra Pradesh, Kerala, Karnataka, Tamilnadu, Daman and Lakshadweep islands. The plant commonly known as Hadjod in Hindi and Kandvel in Marathi. The plant is perennial succulent climber having quadrangular stem with nodes and internodes. Phytochemical studies on showed that the plant contains triterpenes including α- and β- amyrins, β- sitosterol, ketosteroids, phenols, tannins, carotene and vitamin C. Several other constituents such as flavonoids quercetin and kampferol, and stilbene derivatives, quadrangularins and many others e.g. resveratol, piceatanon, pallidol, and phytosterols have been isolated from plant. Stem extract contains a high percentage of calcium ions and phosphorus, both essential for bone growth. Whole plant and plant parts are used in various medicinal formulations. The plant is traditionally known for its bone healing property. It is also used in cure of osteoporosis, jaundice, Gonorrhoea, Syphilis, bleeding, epistaxis, menorrhagia, anorexia, indigestion, gastritis, worm infection, diarrhoea, malabsorption, diseases in bowels, haemorrhoids, anaemia, jaundice, ascites, hernia, bronchial asthma, cough, whooping-cough, fever, oedema, urine retention, earache, otorrhea, deafness, toothache, pain, diseases. It also shows antidiabetic properties and can be used to reduce weight. Studies have proved antimicrobial activities against various fungi and bacteria.