UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRDI06075


Registration ID:
227494

Page Number

384-388

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Title

STUDIES IN ANTIFUNGAL ACTIVITY OF N-HETEROCYCLIC SUBSTITUTED HYDRAZONE SCHIFF’S BASES.

Abstract

In the present study, we have reported the synthesis, spectral studies and biological evolution of substituted hydrazone schiff’s bases derivatives of benzothiazolyl and benzimidazolyl for antifungal activity. In the present research series of 2-[1-(Benzothiazole-2-yl hydrazono)-ethyl]-5-methyl phenol, 2-(Benzothiazole-2-yl hydrazono)-methyl)- phenol, N-Benzothiazole-2-yl-N-(1-4-chloro-phenyl)-ethylidene]-hydrazine ,2-[1-H-Benzimidazole-2-yl hydrazono)-methyl]-4-methyl phenol were synthesized by green chemistry technique. Structures of all the newly synthesized compounds were confirmed by their IR, 1H-NMR and CHN analysis .The antifungal activities of these synthesized compounds are done by cup plate method The fresh cultures of Candida albicans (NCIM 3103). Present work was based on the synthesis of substituted benzothiazole derivatives in order to find out the antifungal activity against C. albicans and Pityrosporium ovalue. since Candida albicans is mainly responsible for skin infection, especially in the epithelial cells of the vagina. Candida albicans is a yeast that commensally inhabits the human body and can cause opportunistic or pathogenic infections.

Key Words

Antifungal activity; Cup plate method, Skin infection, 2-substituted benzothiazole.

Cite This Article

"STUDIES IN ANTIFUNGAL ACTIVITY OF N-HETEROCYCLIC SUBSTITUTED HYDRAZONE SCHIFF’S BASES. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.384-388, February-2020, Available :http://www.jetir.org/papers/JETIRDI06075.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"STUDIES IN ANTIFUNGAL ACTIVITY OF N-HETEROCYCLIC SUBSTITUTED HYDRAZONE SCHIFF’S BASES. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp384-388, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06075.pdf

Publication Details

Published Paper ID: JETIRDI06075
Registration ID: 227494
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 384-388
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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