UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
Call for Paper
Volume 11 | Issue 3 | March 2024

JETIREXPLORE- Search Thousands of research papers



WhatsApp Contact
Click Here

Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

Unique Identifier

Published Paper ID:
JETIRDI06118


Registration ID:
227447

Page Number

594-600

Share This Article


Jetir RMS

Title

EVALUATION OF ANTIBACTERIAL ACTIVITY OF CARDIOSPERMUM HALICACABUM AGAINST CLINICAL ISOLATES OF OTITIS MEDIA.

Abstract

India is virtually herbarium of the world. India possesses all types of climatic conditions varying from cold temperature in the Himalayas to tropical in south for the growth of a variety of medicinal and aromatic plants. India, with her varied climatic conditions and topography has considered as “Botanical Garden of the World”. In the present study the phytochemical study, antioxidant activity and in vitro antibacterial activity of acetone, methanol and chloroform extracts of Cardiospermum halicacabum leaves were investigated. Cardiospermum halicacabum is a climber belongs to the family Sapindaceae. The plant is a twinner, pubescent or nearly glabrous annual or perennial. This plant exhibited a wide range of biological and pharmacological properties. Phytochemical analysis revealed the presence of alkaloids, tannins, saponins and flavonoids in leaves of C. halicacabum. Acetone extract of C. halicacabum showed 24.05% free radical scavenging at 50µg/ml. The extracts were screened for in vitro antibacterial activity against selected otitis media pathogens including S. aureus, P. aeruginosa, E. coli, K. pneumonia and S. pneumonia by disc diffusion method and acetone extract was predominant. Acetone extract of C. halicacabum inhibited 100% isolates of S. pneumonia and E coli, 90% isolates of P. aeruginosa, 79% K. pneumoniae and 97% isolates of S. aureus with effective zone range of 15-30 mm and MIC range was 08-32 mg/ml. Present study justifies the claimed uses of C. halicacabum in the Indian traditional system of medicine to treat various diseases. However, as the toxic effects of plant extracts were not tested in present study In future research is required to determine which chemicals are effective which will provide valuable clues for developing herbal drugs for treatment of otitis media.

Key Words

Otitis media, Cardiospermum halicacabum, Antimicrobial activity.

Cite This Article

"EVALUATION OF ANTIBACTERIAL ACTIVITY OF CARDIOSPERMUM HALICACABUM AGAINST CLINICAL ISOLATES OF OTITIS MEDIA. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.594-600, February-2020, Available :http://www.jetir.org/papers/JETIRDI06118.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"EVALUATION OF ANTIBACTERIAL ACTIVITY OF CARDIOSPERMUM HALICACABUM AGAINST CLINICAL ISOLATES OF OTITIS MEDIA. ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp594-600, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06118.pdf

Publication Details

Published Paper ID: JETIRDI06118
Registration ID: 227447
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 594-600
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


Preview This Article


Downlaod

Click here for Article Preview

Download PDF

Downloads

0003092

Print This Page

Current Call For Paper

Jetir RMS