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March-2020
eISSN: 2349-5162
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC Approved Journal no 63975(19)
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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Published Paper ID:
JETIRDN06043
Registration ID:
229497
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Title
Synthesis and Antimicrobial Activity of Pyrazolo[4,5-e] Pyrimido[2,1-b]Pyrazines
Abstract
Based on the potent biological activity of pyrazolo derivatives, we carried out synthesis of 3-amino-4-imino-2-N-(substituted)pyrazolo[4,5-e]pyrimido[2,1-b] pyrazines (3a-j) have been reported from condensation of 3-cyano-4-imino-2-(methylthio)-4H-pyrimido[1,2-a]pyrazine (1) and substituted hydrazines and hydrazine benzothiazole (2a-j) using dimethyl formamide as reaction solvent and anhydrous K2CO3 as reaction catalyst. These synthesized compounds were further screened for antibacterial activity and cytotoxicity study.
Key Words
Pyrimido pyrazine, substituted hydrazines, anhydrous K2CO3.
Cite This Article
"Synthesis and Antimicrobial Activity of Pyrazolo[4,5-e] Pyrimido[2,1-b]Pyrazines", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.189-192, March-2020, Available :http://www.jetir.org/papers/JETIRDN06043.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"Synthesis and Antimicrobial Activity of Pyrazolo[4,5-e] Pyrimido[2,1-b]Pyrazines", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp189-192, March-2020, Available at : http://www.jetir.org/papers/JETIRDN06043.pdf
Publication Details
Published Paper ID: JETIRDN06043
Registration ID: 229497
Published In: Volume 7 | Issue 3 | Year March-2020
Page No: 189-192
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIRDN06043
Published Paper PDF: https://www.jetir.org/papers/JETIRDN06043
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