• Zainib Hilal
• Rishi Kant

Piperazine core has the unique structural feature which is widely exploited in medicinal chemistry. Substitution on piperazine provides a way to build library of compound which are bioactive. Bioactivity of piperazine core has been utilised in manufacturing of many classes of drugs which are commercially available. Structures of these drugs contain piperazine unit with either one side substitution or both, thus this small unit provide a unique way to build a huge library of compounds. Therapeutic action of these drugs provides significant breakthrough in providing the mechanism for prevention of fatal diseases. Here we present a few classes of drugs containing piperazine moiety and discussed their therapeutic action in the living system.

Investigation on the role of Piperazine, a six membered heterocycle at the centre of many unique classes of drugs

"Investigation on the role of Piperazine, a six membered heterocycle at the centre of many unique classes of drugs", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 10, page no.144-153, October 2018, Available :http://www.jetir.org/papers/JETIRDQ06020.pdf

"Investigation on the role of Piperazine, a six membered heterocycle at the centre of many unique classes of drugs", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 10, page no. pp144-153, October 2018, Available at : http://www.jetir.org/papers/JETIRDQ06020.pdf