• Surajmohon
• Daljeet Singh Dhanjal
• Reena Singh
• Chirag Chopra

Cells cannot divide countless times and enter the resting period or senescence before death. Sometimes cells fail to develop senescent state resulting in the production of a large group of cells. This uncontrolled division of cell leads starts with immortalisation, which then leads to tumorigenesis. Cell immortalisation and tumour formation are related to various enzyme activity and molecular passage in our body. This paper mainly reviews the various molecular events involved in apoptosis, tumour formation, de-differentiation, redifferentiation, and senescence. Furthermore, it also discusses the link between immortalisation and telomerase activity in a cell.

Cells, Cell Immortalization, Telomerase, Tumor formation, Tumorigenesis

"The Link Between Cellular Immortalization and Tumorigenesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 1, page no.453-456, January 2019, Available :http://www.jetir.org/papers/JETIRDW06075.pdf

"The Link Between Cellular Immortalization and Tumorigenesis", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 1, page no. pp453-456, January 2019, Available at : http://www.jetir.org/papers/JETIRDW06075.pdf