UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 5 Issue 9
September-2018
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRFH06048


Registration ID:
318827

Page Number

282-286

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Title

Pharmacogenomics of Drug Transporters: A Comprehensive Review

Abstract

Pharmacogenomics attempts to explore people who are susceptible to toxicity and poor response to conventional anticancer medication dosages. The therapeutic relevance of pharmacogenomics research that has already been done is still a hot subject. Though protein pharmacogenomics is well-studied in stage 1, the clinical consequences of stage II genetic diversity in enzymes or drug transporters are less well understood. The effect of pharmacokinetics, particularly the danger of some clinically variable medicinal medicines, on membrane transporters has grown in the last ten years. Polymorphisms can have diverse, sometimes even conflicting, pharmacokinetic and pharmacodynamics consequences in various cancers in response to various medicines, according to studies of different regimens and tumour types. More thorough knowledge on the various polymorphisms in drug-metabolizing enzymes and drug transporters is required for the practical use of pharmacogenomics in cancer treatment. Before personalized therapy may be used on a regular basis, a better knowledge of the intricacies of pharmacogenomics is required. This paper provides an overview on pharmacogenomics of drug transporters.

Key Words

Anticancer, ABC, ATP-Binding, Drug Transporters, Pharmacogenomics.

Cite This Article

"Pharmacogenomics of Drug Transporters: A Comprehensive Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 9, page no.282-286, September 2018, Available :http://www.jetir.org/papers/JETIRFH06048.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Pharmacogenomics of Drug Transporters: A Comprehensive Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 9, page no. pp282-286, September 2018, Available at : http://www.jetir.org/papers/JETIRFH06048.pdf

Publication Details

Published Paper ID: JETIRFH06048
Registration ID: 318827
Published In: Volume 5 | Issue 9 | Year September-2018
DOI (Digital Object Identifier):
Page No: 282-286
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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