• Prajakta N. Bathe
• Vinod K. Nagale
• Sneha W. Wagh
• Snehal G. Rodge

Lysozyme is a naturally occurring enzyme found in bodily secretions such as tears, saliva, and milk. It functions as an antimicrobial agent by cleaving the peptidoglycan component of bacterial cell walls, which leads to cell death. In present study we chose 20 Vertebrate Species including 1 amphibian, 3 actinopterygii, 7 aves and 9 mammals. Amino acid sequences of Lysozyme from 20 vertebrates were derived from National Center for Biotechnology Information database. Phylogenetic analysis and estimation were performed using MEGA program, and neighbor-joining tree was constructed by this software. In this computational study, the phylogenetic tree of Lysozyme has been investigated. Therefore, dendrograms of lysozyme were depicted. From the result of present phylogenetic study of vertebrate Lysozyme, it concluded that the amino acid sequences among different vertebrate species shows slight to moderate differences without affecting its functions.

Lysozyme, Antimicrobial activity, MEGA, Phylogeny, Vertebrate

"Phylogenetic Analysis of Vertebrate Lysozyme", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 5, page no.198-202, May-2022, Available :http://www.jetir.org/papers/JETIRFO06032.pdf

"Phylogenetic Analysis of Vertebrate Lysozyme", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 5, page no. pp198-202, May-2022, Available at : http://www.jetir.org/papers/JETIRFO06032.pdf