• Dr. V. A. Sadafale

Digestion in the stomach results from the action of gastric fluid, which includes secretions of digestive enzymes, mucous, and hydrochloric acid. The acidic environment of the stomach makes it possible for inactive forms of digestive enzymes to be converted into active forms (i.e. pepsinogen into pepsin), and acid is also needed to dissolve minerals and kill bacteria that may enter the stomach along with food. However, excessive acid production (hyperacidity) results in the unpleasant symptoms of heartburn and may contribute to ulcer formation in the stomach lining. An Antacid is any substance, generally a base or basic salt, which neutralizes stomach acidity. They are used to relieve acid indigestion, upset stomach, sour stomach, and heartburn. The present study aimed at assessing the acid neutralizing capacity of commercially available antacids. The acid neutralizing capacities were analyzed by back titration method. In this method the antacid is first made to react with excess hydrochloric acid (main constituent of gastric juice), which is titrated against standard sodium hydroxide and the ability of the antacid to neutralize the acid is noted, which is its antacid value. Digene showed good antacid property compared to others. However, taking into account the dangers of the overuse of these medications; one can think of traditional remedies as an alternate solution for mild symptoms.

Antacid, Acid neutralizing capacity, Digene, Antacid, Gastric fluid.

"Assessment of acid neutralizing capacity of commercially available antacids", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 5, page no.288-290, May-2022, Available :http://www.jetir.org/papers/JETIRFO06049.pdf

"Assessment of acid neutralizing capacity of commercially available antacids", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 5, page no. pp288-290, May-2022, Available at : http://www.jetir.org/papers/JETIRFO06049.pdf