• Dr Santosh Kumar Singh

Diabetes mellitus refers to a group of metabolic disorders that leads to high blood sugar level. The mixture of herbs is needed instead of mono-drug therapy for the control of the condition, for example, multifactorial metabolic disorders, diabetics, which have multiple complications, including hyperlipidemia, hepatic toxicity, immunodeficiency etc. The present paper deals with the development of polyherbal formulation for the treatment of diabetes, wherein different herbs i.e. Glycine max extract, Zingiber officinalis (rhizome) and curcumin (a phenolic antioxidant) are mixed with sodium Lauryl sulfate and were subjected under a method for the preparation of the herbal solution. The formulation was then analyzed for their in-vitro cytotoxicity wherein it was found that the herbal formulation does not showed any cytotoxicity after 24 hrs. Similarly, glucose utilization HepG2 cells was also determined wherein it was observed that the cells were able to utilize higher concentration of glucose. Protein glycation assay was also performed for the formulation wherein it was observed that the extract exhibited protein glycation of 24.5%.

Curcumin, Diabetes, Glycine Max Extract, Zingiber Officinalis

"Herbal Anti-Diabetic Formulation for Diabetes: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 6, page no.60-67, June-2018, Available :http://www.jetir.org/papers/JETIRFR06011.pdf

"Herbal Anti-Diabetic Formulation for Diabetes: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 6, page no. pp60-67, June-2018, Available at : http://www.jetir.org/papers/JETIRFR06011.pdf