• M. Noor Rezwana
• Dr. Kamlesh Kumar

The goal of this study is to evaluate the oxidative and antioxidative state of diabetic and non-diabetic individuals with cataracts, as well as healthy controls. In all, 149 people participated in this analysis. Blood samples were collected from people who had diabetic cataracts, people who had age-related cataracts, and those who were healthy enough to serve as a control group. In this study, we evaluated total oxidant status (TOS), total antioxidant status (TAS), total thiol levels (TTLs), and paraoxonase 1 (PON1) in the blood. TTLs were significantly lower in diabetes cataract patients compared to both the nondiabetic cataract patients and the control group. Patients with diabetic cataract also had significantly reduced plasma PON1 levels compared to the control group. Both TAS and TOS levels were similar between groups, without any statistical significance. This research shows that individuals with diabetes cataracts had significantly lower serum TTLs and serum PON1 activity than controls. These results point to problems with the body's antioxidant defenses, which may be linked to cataract formation.

Oxidative status, antioxidative status, diabetic cataract

"ANALYTICAL STUDY ON OXIDATIVE AND ANTIOXIDATIVE STATUS IN PATIENTS WITH DIABETIC CATARACTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 10, page no.157-165, October-2022, Available :http://www.jetir.org/papers/JETIRFU06019.pdf

"ANALYTICAL STUDY ON OXIDATIVE AND ANTIOXIDATIVE STATUS IN PATIENTS WITH DIABETIC CATARACTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 10, page no. pp157-165, October-2022, Available at : http://www.jetir.org/papers/JETIRFU06019.pdf