UGC Approved Journal no 63975(19)

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Published in:

Volume 10 Issue 4
April-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRFW06001


Registration ID:
512370

Page Number

1-8

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Title

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME NOVEL DERIVATIVES OF 2- MERCAPTOBENZIMIDAZOLE AS POSSIBLE ANTIMICROBIAL AGENTS

Abstract

We report a novel scaffold of 2-substituted mercaptobenzimidazole derivatives designed as a potent antimicrobial activity. Ten derivatives were synthesised, spectral characterized and evaluated for their antimicrobial and antifungal activity conducted by disc diffusion method. The synthesized derivatives HC-3, HC-5, HC-7, HC-8, HC-10 exhibited poor activity at 50 μg/ml, but at 100 μg/ml they have shown moderate activity against S.aureus, and moderate activity against E.coli whereas HC-3, HC-5, HC-7, HC-8, and HC-10, showed highest degree of inhibition at 250μg/ml and 500μg/ml against C.albicans when compared with standard one.

Key Words

mercaptobenzimidazole, degree of inhibition, antimicrobial and antifungal

Cite This Article

"SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME NOVEL DERIVATIVES OF 2- MERCAPTOBENZIMIDAZOLE AS POSSIBLE ANTIMICROBIAL AGENTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.1-8, April-2023, Available :http://www.jetir.org/papers/JETIRFW06001.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF SOME NOVEL DERIVATIVES OF 2- MERCAPTOBENZIMIDAZOLE AS POSSIBLE ANTIMICROBIAL AGENTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp1-8, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06001.pdf

Publication Details

Published Paper ID: JETIRFW06001
Registration ID: 512370
Published In: Volume 10 | Issue 4 | Year April-2023
DOI (Digital Object Identifier):
Page No: 1-8
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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