• Vishal Rathod
• Alok Kadam
• Arjun Bembade
• O.G. Bhusnure

Ranolazine Hydrochloride (RAN) chemically is a piperizine derivative used as an anti-aginal drug. Ranolazine is used for the treatment of cardiac ischemia and it effects sodium dependent calcium channel during myocardial ischemia. Ranolazine indirectly prevents the calcium overload that causes cardiac ischemia. Ranolazine Hydrochloride is indicated for the treatment of chronic angina. Ranolazine may be used with beta-blockers, nitrates, calcium channel blockers, antiplatelet therapy, lipid-lowering therapy, ACE inhibitors, and angiotensin receptor blockers. This review article represents the various analytical methods which have been reported for estimation of ranolazine in synthetic mixture. Chromatographic methods like HPLC, RP-HPLC, HPTLC, GC, LC-MS, LCMS/MS were reported.

Ranolazine hcl, anti aginal drug,Hplc, Rp hplc,GC, ace inhibitor

"“DEVELOPMENT AND VALIDATION OF INDICATING INSTRUMENTAL METHOD FOR ESTIMATION OF RANOLAZINE IN BULK AND TABLET DOSAGE FORM”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.17-39, April-2023, Available :http://www.jetir.org/papers/JETIRFW06004.pdf

"“DEVELOPMENT AND VALIDATION OF INDICATING INSTRUMENTAL METHOD FOR ESTIMATION OF RANOLAZINE IN BULK AND TABLET DOSAGE FORM”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp17-39, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06004.pdf