• Pawan P. Jadhav
• S.N.Nagoba

The current review on in situ gelling systems becomes one of the most popular and prominent. It had a tremendous potential advantage of delivery systems due to many benefits like easy to use, simple manufacturing, improve both adherence and patient comfort by minimizing the frequency of drug administration by its unique characteristics feature of sol to gel transition. The drawbacks associated with conventional systems of both solutions and gels, such as accurate dosing, ease of administration overcome by using in situ gelling systems. This review covers introduction, polymers used in in situ gel, in-situ gel for different diseases, Advantages and Disadvantages, preparation and evaluation, Recent Advancement.

in-situ gel, natural and synthetic polymers, drug delivery systems, sol to gel form, onychomycosis.

"GENERAL REVIEW ON IN-SITU GELLING DRUG DELIVERY SYSTEM FOR TREATMENT OF VARIOUS DISEASES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.361-366, April-2023, Available :http://www.jetir.org/papers/JETIRFW06047.pdf

"GENERAL REVIEW ON IN-SITU GELLING DRUG DELIVERY SYSTEM FOR TREATMENT OF VARIOUS DISEASES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp361-366, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06047.pdf