UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 4
April-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRFW06060


Registration ID:
512298

Page Number

455-464

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Title

Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction

Abstract

The Aza Michael reaction is widely recognized as one of the most important carbon- nitrogen bond forming reactions in organic synthesis 2. In general this transformation is a heteroatom (Nitrogen) nucleophilic (donor addition to a β-carbon of electro poor alkenes accepter) giving a stabilized carbanion intermediate, which after protonation with another electrophile furnishes the final addition product. The obtained β-amino ketones owing to their wide range of biological activities7 and pharmacological properties3-4. The synthesis of β-amino carbonyl compounds has become a field of increasing interest in organic synthesis during the past few decades.4 Carbonyl compounds (aza- Michael addition) are one of the simplest and most effective methods for preparing β- amino carbonyl compound. In recent years a number of catalysts such as Sml2 CuO7f2, Bi (NO3), Bi (OTF)2, LiClO4, FeCl3-6H2O. TMSCI, boric acid and clay have been developed for this reaction

Key Words

Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction

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"Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.455-464, April-2023, Available :http://www.jetir.org/papers/JETIRFW06060.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp455-464, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06060.pdf

Publication Details

Published Paper ID: JETIRFW06060
Registration ID: 512298
Published In: Volume 10 | Issue 4 | Year April-2023
DOI (Digital Object Identifier):
Page No: 455-464
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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