• Dr. Jaishri Somwanshi
• Dr. M.B Swami

The Aza Michael reaction is widely recognized as one of the most important carbon- nitrogen bond forming reactions in organic synthesis 2. In general this transformation is a heteroatom (Nitrogen) nucleophilic (donor addition to a β-carbon of electro poor alkenes accepter) giving a stabilized carbanion intermediate, which after protonation with another electrophile furnishes the final addition product. The obtained β-amino ketones owing to their wide range of biological activities7 and pharmacological properties3-4. The synthesis of β-amino carbonyl compounds has become a field of increasing interest in organic synthesis during the past few decades.4 Carbonyl compounds (aza- Michael addition) are one of the simplest and most effective methods for preparing β- amino carbonyl compound. In recent years a number of catalysts such as Sml2 CuO7f2, Bi (NO3), Bi (OTF)2, LiClO4, FeCl3-6H2O. TMSCI, boric acid and clay have been developed for this reaction

Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction

"Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.455-464, April-2023, Available :http://www.jetir.org/papers/JETIRFW06060.pdf

"Synthesis of β-amino carbonyl compounds by using Aza- Michael reaction", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp455-464, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06060.pdf