UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 4
April-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRFW06086


Registration ID:
515218

Page Number

646-649

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Title

The Hydrogen bond in Rasagiline Mesylate drug substance interaction with moisture studies by FTIR, XRD, and TGA

Abstract

This article mainly reports the Inductive effect on Rasagiline Mesylate drug substance by FTIR Spectroscopy. The Inductive effect is a temporary effect that produced a partial shifting of σ electrons towards a more electronegative atom of σ bond. This means σ (or single-bond electrons) shifts towards a more electronegative atom. Because of this, partial charges develop, the OH group from the water molecule attacking to the carbon carbon triple bond to form carbon double bond and the molecule gets Partial charge developed and it is a temporary effect, so once the water is removed, the partial charge removed and molecule goes back to its original state. Due to this, here there is no shifting of the Carbon carbon triple bond to the carbon carbon double bond take place and resulting in The IR spectra showing two vibration frequencies in the region of 3219.20 cm.-1 and 3278.99 cm.-1 Sample treated with a mixture of Ethyl acetate and Isopropyl alcohol, followed by drying at 105°C does not involve in the Inductive effect. And IR spectra show one vibration frequency at 3278.99cm-1 and there is no shifting of carbon carbon triple bond to carbon carbon double bond take place and does not involve the Inductive effect.

Key Words

Inductive Effect, Hygroscopic, FTIR spectroscopy, Rasagiline Mesylate.

Cite This Article

"The Hydrogen bond in Rasagiline Mesylate drug substance interaction with moisture studies by FTIR, XRD, and TGA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.646-649, April-2023, Available :http://www.jetir.org/papers/JETIRFW06086.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"The Hydrogen bond in Rasagiline Mesylate drug substance interaction with moisture studies by FTIR, XRD, and TGA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. pp646-649, April-2023, Available at : http://www.jetir.org/papers/JETIRFW06086.pdf

Publication Details

Published Paper ID: JETIRFW06086
Registration ID: 515218
Published In: Volume 10 | Issue 4 | Year April-2023
DOI (Digital Object Identifier):
Page No: 646-649
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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