• Shital S. Phuse
• Zia H. Khan

Aims and objectives: Cosmos is a medicinal plant which has long traditional use in Brazil and Mexico for treatment of several diseases. Hence the present attempt had been made to describe antioxidant properties and hemolytic effect of polar and non polar extracts of Cosmos sulphureus. Flower part of the plant was studied. Materials and Methods: Flowers were collected, air dried and individually subjected to extraction with ethyl acetate and acetone. These extracts were assessed for phenol and flavonoid contents. Further evaluations was done by using DPPH (2, 2-diphenyl-1-picrylhydrazyl) method and anti-hemolytic activity assay against standard Ascorbic acid and quercetin respectively. Result and conclusion: IC50 values for antioxidant potential of ethyl acetate and acetone flower extracts were found to be 146.84µg/ml and 74.66µg/ml respectively. IC50 values for antihemolytic activity were shown to be 154.44 µg/ml of ethyl acetate and 165.6 µg/ml of acetone flower extracts respectively. The present work revealed that flower part of acetone extract possesses maximum percentage of free scavenging activity and exhibits highest antihemolytic activity. This observation revealed that extracts exhibited great potential antioxidant property and antihemolytic activity. Thus it can be consider as very useful plant to treat and control several diseases.

Cosmos sulphureus, Extracts, Antioxidants, Anti hemolysis, DPPH, Ascorbic acid, Quercetin

"EVALUATION FOR ANTIOXIDANT POTENTIAL AND HEMOLYTIC EFFECT OF COSMOS SULPHUREUS FLOWER EXTRACTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.29-35, December-2018, Available :http://www.jetir.org/papers/JETIRS006005.pdf

"EVALUATION FOR ANTIOXIDANT POTENTIAL AND HEMOLYTIC EFFECT OF COSMOS SULPHUREUS FLOWER EXTRACTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp29-35, December-2018, Available at : http://www.jetir.org/papers/JETIRS006005.pdf