• Shilpa Subhash Burele

Gram negative hospital acquired infection are a major problem since last two decades Acinetobacter baumanii has emerged as a highly trouble pathogen for many institutions globally. As a consequence of its immense ability to acquired antibiotic drug resistance determinant .It has justifiably been propelled to the fore front of scientific attention. Rapid spread of multidrug resistant isolate causing infection. Acinetobacter baumannii clinical strains, were selected from a new phage library for further characterization. The complete genomes of the two phages were analyzed. Both phages are characterized by broad host range and essential features of potential therapeutic phages, such as short latent period (27 and 21 min, respectively), high burst size (125 and 145, respectively), stability of activity in liquid culture and low frequency of occurrence of phage-resistant mutant bacterial cells. Genomic analysis showed that while bacteriophage with resemblance to some unclassified Pseudomonas aeruginosa phages, The newly isolated phages can serve as control A. baumannii infections.

Acinetobacter isolates, Bacteriophages, Multidrug-resistant (MDR)

"Susceptibility to Environmental Phages With clinical Antibiotic-resistant Acinetobacter baumannii than Antibiotic-sensitive Strains", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.5, Issue 12, page no.36-43, December-2018, Available :http://www.jetir.org/papers/JETIRS006006.pdf

"Susceptibility to Environmental Phages With clinical Antibiotic-resistant Acinetobacter baumannii than Antibiotic-sensitive Strains", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.5, Issue 12, page no. pp36-43, December-2018, Available at : http://www.jetir.org/papers/JETIRS006006.pdf