UGC Approved Journal no 63975(19)

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Published in:

Volume 10 Issue 8
August-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIRTHE2055


Registration ID:
522518

Page Number

d552-d587

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Title

“SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY EVALUATION OF 4-AMINOQUNOLINE 1, 2, 4-TRIAZOLE DERIVATVES”

Abstract

Xanthenes’ derivative is nitrogen containing heterocyclic aromatic compounds. Various heterocyclic compounds have show stimulation of cardiac muscle, enhanced dieresis, stimulation of CNS and finally a soothing relaxation of Bronchi and the coronary arteries. Literatures in the recent past reveal that some theophylline derivative possesses antibacterial and enhance Antitussive and Bronchodilator activity. The synthesis of substituted 1,3-Dimethylxanthine derivative consist of the following steps which are as follows. Step-I: Synthesis of the 7-(undec-10-ene)theophylline Step-II: Synthesis of the 8-(7-Chloroquinoline)-7-(undec-10-ene)theophylline Step-III: Synthesis of 7-(7-Chloroquinoline)theophylline All the synthesized compounds by the above described method result in products with good yields. IR, 1H NMR and Mass spectroscopic analysis conformed the structures of new synthesized compounds. The newly synthesized compounds were screened for their Bronchodilator activities by using Theophylline as standard and are found to be effective Bronchodilator agent.

Key Words

Synthesis of the 8-(7-Chloroquinoline)-7-(undec-10-ene)theophylline

Cite This Article

"“SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY EVALUATION OF 4-AMINOQUNOLINE 1, 2, 4-TRIAZOLE DERIVATVES”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 8, page no.d552-d587, August-2023, Available :http://www.jetir.org/papers/JETIRTHE2055.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"“SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY EVALUATION OF 4-AMINOQUNOLINE 1, 2, 4-TRIAZOLE DERIVATVES”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 8, page no. ppd552-d587, August-2023, Available at : http://www.jetir.org/papers/JETIRTHE2055.pdf

Publication Details

Published Paper ID: JETIRTHE2055
Registration ID: 522518
Published In: Volume 10 | Issue 8 | Year August-2023
DOI (Digital Object Identifier):
Page No: d552-d587
Country: JAUNPUR, UTTAR PRADESH, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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