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Published in:

Volume 2 Issue 5
May-2015
eISSN: 2349-5162

Unique Identifier

JETIR1701124

Page Number

537-541

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Title

NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS

ISSN

2349-5162

Cite This Article

"NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.2, Issue 5, page no.537-541, May-2015, Available :http://www.jetir.org/papers/JETIR1701124.pdf

Abstract

Two simple and sensitive Spectrophotometric methods (A and B) for the determination of Trimetazidine dihydrochloride in Bulk samples and pharmaceutical formulations are described. Method A is based on oxidative coupling reaction using 2,6 dichloro Quinine -4 – Chlorimde (DCQC). Which yield reddish coloured complex is measured at max 520 nm. And method B is based on the formation of the blue coloured species, which the drug is treated with folin-cioclteu (FC) reagent under alkaline conditions with an absorption maximum of max 770nm. The results obtained by the proposed methods were good agreement with the labelled amounts

Key Words

Trimetazidine, dihydrochloride, Dictloro quinine – 4 chloramide (DCQC), folin-cioclteu (FC) reagent

Cite This Article

"NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.2, Issue 5, page no. pp537-541, May-2015, Available at : http://www.jetir.org/papers/JETIR1701124.pdf

Publication Details

Published Paper ID: JETIR1701124
Registration ID: 221916
Published In: Volume 2 | Issue 5 | Year May-2015
DOI (Digital Object Identifier):
Page No: 537-541
ISSN Number: 2349-5162

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Cite This Article

"NEW ANALYTICAL METHODS FOR THE ASSAY OF TRIMETAZIDINE DIHYDROCHLORIDE IN PURE AND PHARMACEUTICAL FORMULATIONS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.2, Issue 5, page no. pp537-541, May-2015, Available at : http://www.jetir.org/papers/JETIR1701124.pdf




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