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Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

Unique Identifier

JETIRDI06093

Page Number

480-482

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Title

Biological Evaluation of Some 6-dihydro-2, 4- di(substitutedphenyl)-pyrimid-5-one derivetives

ISSN

2349-5162

Cite This Article

"Biological Evaluation of Some 6-dihydro-2, 4- di(substitutedphenyl)-pyrimid-5-one derivetives ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.480-482, February-2020, Available :http://www.jetir.org/papers/JETIRDI06093.pdf

Abstract

Microwave radiation facilitated synthesis of di(substitutedphenyl)-pyrimid-5-one (Ia-Ij) by condensation of substituted amide(0.01M), aromatic aldehyde (0.015M)and amino acid(0.01M) in presence of metal salt as a catalyst. The reaction mixture was irradiated under scientific microwave oven for 1-2 minutes. The synthesized compounds were characterized by elemental analysis and IR, NMR, CMR, UV and Mass spectrum. Melting point are uncorrected and carried out on Thieles apparatus.The synthesized compound was screened for antimicrobial activities against Proteus vulgaris, Staphylococcus aureus, Escherichia coli and Salmonella typhi. The compounds showed good to moderate activity against the pathogens.

Key Words

Condensation, Pyrimidine, microwave irradiation, Antimicrobial activities.

Cite This Article

"Biological Evaluation of Some 6-dihydro-2, 4- di(substitutedphenyl)-pyrimid-5-one derivetives ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp480-482, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06093.pdf

Publication Details

Published Paper ID: JETIRDI06093
Registration ID: 227474
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 480-482
ISSN Number: 2349-5162

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Cite This Article

"Biological Evaluation of Some 6-dihydro-2, 4- di(substitutedphenyl)-pyrimid-5-one derivetives ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp480-482, February-2020, Available at : http://www.jetir.org/papers/JETIRDI06093.pdf




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