• MR.KSHATRIYA PRAVIN JAMNADAS
• MR. SHINDE JITENDRA V.
• MISS. BHOSALE AISHWARYA RAJENDRA

Effective targeted drug delivery system has been a dream for an extended time, however it’s been mostly annoyed by the complicated chemistry that’s concerned within the development of latest systems. Topical drug delivery system has several issues like poor porosity, skin irritation , hypersensitive reactions etc. major issues of new developed chemical entities is their poor solubility in water and pharmacokinetic problems. These poorly-water soluble medication show several issues in formulating them in typical indefinite quantity forms and therefore the crucial issues associated is its terribly low bioavailability. The invention of nanosponge has become a big step towards overcoming these issues. Nanosponge is small sponges with a few virus (250nm-1µm), which may be crammed with a good kind of medication. Nanosponge play very important role in targeting medication delivery in a very controlled manner. This sponge will flow into round the body till move with specific target site and stick on the surface and cathartic drug in controlled manner each oleophilic and deliquescent medication square measure incorporated in nanosponge vital characteristics of those sponges square measure their solubility in liquid from and appropriate for the medication with poor solubility. This review is specializing in the preparation technique, applications of nanosponge, consider the sector of drug delivery.

NANOSPONGE, POOR SOLUBILITY, POLYMERS, SYNTHESIS PREPARATION.

"NANOSPONGE: NOVEL EMERGING DRUG DELIVERY SYSTEM.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.1337-1351, October-2020, Available :http://www.jetir.org/papers/JETIR2010174.pdf

"NANOSPONGE: NOVEL EMERGING DRUG DELIVERY SYSTEM.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp1337-1351, October-2020, Available at : http://www.jetir.org/papers/JETIR2010174.pdf